2014 TS Will Not Open - error code 104

Replaced hard drive on main PC acting as server for small office network of 3 PCs.  The TS program will not open, and is therefore not accessible by two other PCs.  Keep getting the following message:

Could not open T:\LCNSREGS.DAT. The Read Only file attribute is set. The file cannot be modified.

  Area: Streams

Error Code: 104

 Class: tHdrFileStreamExceptionC

  Version: 22.0.2.256

 Date: 2/9/2015

 Time: 8:56:04 AM

  Exception tHdrFileStreamExceptionC in module Timeslip.exe at 000EDF5C.